By Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)
There is an Inca incantation which acknowledged stated approximately: "Lord, provide me non secular peace in order that i will acquiesce to what i will not swap, provide me braveness in order that i will swap what i will be able to swap, and provides me knowledge in order that i will be able to distinguish one from the opposite. " evidently, this incantation should be usually repeated by means of any gerontologist, because it is particularly tough to tell apart getting older from the approaches which counterpoint the organism's viability, getting older from ailments, and the mechanisms of getting older in a variety of species of animals. in line with N. surprise, who compiled a precious bibliography of the works on getting older, greater than 43,000 works on gerontology were released within the final decade. Why will we proceed to disagree with each other and carry that crucial mechanisms are nonetheless principally unknown to us inspite of that move of data and a huge variety of evidence? what's it that we don't comprehend? may it's that we don't be aware of the only real sacramental truth which may clarify every little thing, equivalent to the hormone of getting older, the programmed triggering of a suicide gene, the looks of a distinct poisonous agent within the axoplasmic movement of drugs, and so on? Goethe as soon as wrote scientist often holds definite components, yet regrettably he lacks their sacred link.
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Extra resources for Aging and Life-Prolonging Processes
The occurrences of parkinsonism sharply increase among elderly persons. Cases of parkinsonism are much more common among persons above 60 than 32 General Biology of Vitauct and Aging among young persons. In young persons, this disease is the outcome of either the primary degenerative changes in the subcortical structures or postencephalitic disturbances, while in elderly persons, the vascular factor is mainly responsible for it. The neurophysiological mechanisms of parkinsonism are connected with a disturbance in the motor regulation centres, the striapallidal system, and Substantia nigra.
E. the outcome of the natural sequence of the repression and depression of genes that causes the succession of various stages of aging. Other researchers, however, regard aging as a stochastic process, i. e. the outcome of the natural action of casual damaging factors, including thermal and radiation microeffects, free radicals, active metabolites, and the inert analogues of many other factors which inevitably originate during vital activity. They also include the inevitable "inaccuracies," "blunders" and "errors" of the biological processes which occur during the microintervals of time in microspace and which require very accurate interaction.
13). However, there are contradictory data. According to Ferrendelli and others (1971), brain anoxia for ten seconds caused a greater drop in the A TP level (especially in the striatum) of rats 29 months old than in the level of those 4 months old. Mankovsky and Belonog (1974) observed that the shifts in the EEG were less pronounced in old persons that in young persons during short-term hypoxic hypoxia (the inhalation of a gas mixture with a low oxygen content). According to Timko Aging of the Brain 46 (1971), the rate at which a stimulus is propagated along the arm nerve changes more in young persons than in old persons when the arm is bound by an elastic bandage.